Hyaluronic acid in cosmetics OEM generation of processing the application

Hyaluronic acid believes that many women wanting or often use protect skin to taste the girls heard or read about, it is very widely used in cosmetics OEM generation of processing, is also a very good moisturizing effect of skincare raw material composition. Hyaluronic acid ( HA) , also known as 'hyaluronic acid'. Is a kind of acid mucopolysaccharide, Meyer and others by the United States first isolated from bovine eye in the vitreous material. Biochemical substances, it is a good performance is widely used in pharmaceutical, cosmetic, food, cosmetics and other fields, has a unique moisturizing properties, is one of the popular products biological chemical sector at home and abroad.

hyaluronic acid is a beta - D - N - acetyl glucosamine and beta - D - glucose acid for structural unit in beta 1, 4 glycosidic chain together as a kind of linear polymer acid mucopolysaccharide, its small skin irritation to human body, safe non-toxic. Hyaluronic acid is not only maintain the skin elasticity function, still can lock in a large number of water molecules, has moisturizing effect to the skin.

at present commonly used preparation technology has two types: one is the use of natural ingredients extracted from animal tissue, the main raw material is human umbilical cord, comb and bull 's-eye vitreous, etc. Using acetone or ethanol degreasing, dehydration, drying, materials will be soaked with distilled water, filtering, and then treated with sodium chloride solution and chloroform solution, add the mixture after trypsin heat preservation, with ion exchange agent for processing, finally refined purified hyaluronic acid. The extraction rate is extremely low, only about 1%. Second, the biological fermentation. With glucose as carbon source. After 48 hours in culture fermentation, the fermentation, and filtration to remove mycelium and impurities, then use alcohol precipitation method such as simple operation with high purity of product. Manufactured fermentation of hyaluronic acid, can advantage is to set the molecular weight is designed according to the goods. Strains of fermentation is the key to select, at present more choose streptococcus bacteria etc. Fermentation was still in the stage of research and development in our country, the main use of animal tissue extract hyaluronic acid production, due to the raw material resources are limited, and the preparation of the high cost. Biological fermentation has the products without being limited by the raw material resources, low production cost, simple technology, Without complex purification process) Wait for a characteristic, is the main direction of research and development.

because of hyaluronic acid is hydrophilic and viscoelasticity, in recent years, such as separation methods, test technology, detection means to improve and research deeply, it in clinical medical treatment and diagnosis and cosmetics production has been more and more widely used.

in the early 1980 s, the excellent hyaluronic acid moisturizing function has received extensive attention of the international cosmetics industry. Rich in hyaluronic acid cosmetics can draw a lot of water from genuine leather. At the same time, because the layer in table fat mass barrier effect, can prevent moisture evaporation and loss, to maintain the skin water environment of constant. No matter in low humidity and high humidity conditions, it has the same high hygroscopicity. Therefore, it is treated as a kind of ideal natural insulation factor is widely used in cosmetics, made suitable to different type of skin, climate, environment, use the product. Whether it can be said that the skin of people beautiful and hyaluronic acid plays a decisive role, aging wrinkles appear is hyaluronic acid content lower dermis. Only in terms of its water and nutrition effect, has been hailed as a rational natural moisturizing factor hyaluronic acid. China's vast territory, add hyaluronic acid cosmetics manufacturer is especially suitable for people to use in cold and dry areas. Add hyaluronic acid cosmetics manufacturer on the market at present is increasing.

hyaluronic acid can improve skin physiological conditions, as the dermal collagen and elastic fibers synthetic provide a favorable external environment, strengthen the supply of nutrients, protect skin to raise colour effect. Studies have shown that some of hyaluronic acid can prevent cell enzyme production, reduce the formation of free radicals, prevent free radical damage cells in structure, the ageing caused lipid peroxidation and play an important role in such aspects: low molecular weight hyaluronic acid has anti-inflammatory, inhibiting bacteria produce, keep the skin bright and clean; Provide appropriate places for cell proliferation and differentiation, directly promote cell growth, differentiation, reconstruction and repair, etc. Therefore, it is used as a high grade cream, lotion, lotion, hairdressing fluid, such as lipstick, foundation, cosmetics and toiletries and essential additives to achieve the humidifying tender skin anti-aging and anti-wrinkle moisturizing and anti-inflammatory effect and so on. At present, the cosmetics that contain the ingredients is recognized as 'imitation biochemical products'. Add hyaluronic acid cosmetics has become the mainstream of the international chemical industry products.

has been widely applied because, hyaluronic acid can be unique, with the progress of science and technology, the research beginning, new USES by continual development, the product at home and abroad has become the most potential for development of fine chemicals.

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